Wake Forest is making its first trip to one of college football's great venues as it heads to South Bend, Ind. to take on Notre Dame at Notre Dame Stadium.
Kickoff is set for 3:30 p.m. ET and can be seen nationally on NBC. The game will also be carried live on the Wake Forest Sports Network from IMG College.
This is the second game all-time between to the two private schools.
Notre Dame won last year's meeting 24-17 in Winston-Salem.
The Deacons are in search of their sixth win which would make them bowl eligible for the fifth time in the last seven seasons.
Wake Forest is coming off a tough performance in a 37-6 loss at NC State last Saturday.
State scored the first 17 points and seized all remaining momentum by running the second half kickoff back 100 yards for a touchdown.
Fresh off his record-setting 16 reception game against Boston College, wide receiver Michael Campanaro had five catches against NC State, giving him a school-record 21 receptions in back-to-back contests.
Campanaro also threw the Deacons' only touchdown pass on the day, taking a pitch from quarterback Tanner Price and finding fellow wide receiver Terence Davis for a 39-yard score. That was Campanaro's third touchdown pass of his career.
Defensively, juniors AJ Marshall and Daniel Mack each recorded a career-high 10 tackles in the game.
The Deacons had come into the game allowing an average of 53.5 yards rushing in the previous four games. But NC State running back Shadrack Thornton rolled-up 110 yards on the ground, making him the first back in the series with more than 100 yards in a game since 2005.
The Last Meeting
Notre Dame
24
Wake Forest
17
November 5, 2011
Winston-Salem, N.C.
Wake Forest Comes Up Short in 24-17 Loss to Notre Dame
Notre Dame scored two third-quarter touchdowns to overcome a seven-point halftime deficit and held off Wake Forest the rest of the way to post a 24-17 defeat of the Demon Deacons in front of 36,307 fans, the fourth-largest crowd in BB&T Field history, on Saturday evening.